Extramural Coordinated Funding

UM Submission Instructions: The Missed Vital Sign 2025

Sponsor:	Wellcome Leap (WLeap)
Award Title:	The Missed Vital Sign
Amount:	Award amounts will be dependent on specific proprosalsand work selected for funding.
UM Deadline:	04/30/2025
Sponsor Deadline:	05/16/2025
Description:	The goal of The Missed Vital Sign program is to demonstrate that routine recording, quantifiable measurement, and better treatment options for menstruation can reduce the time a woman experiences heavy menstrual bleeding from 5 years to 5 months. We aim to do this without increasing unwanted surgical intervention or menstrual cycle suppression. To achieve the goals of the program, we seek advances in 3 thrust areas: Thrust 1: A high-performance multivariate tool to identify women who have HMB at levels that would result in iron deficiency, ensuring they access help within 3 months not 3 years. Thrust 2: Identify causal factors for HMB to inform diagnostic development and identify new, precise, non-hormonal therapeutic targets, particularly those that could be self-administered. Thrust 3: Develop and validate patient stratification tools to personalize management when HMB is identified and ensure effective treatment. This would mean women get treatments that work for them within 2 months, not 2 years. Find the full call from Wellcome Leap here
Number of Applicants University is Allowed to submit:	Unlimited
Additional Requirements:	None
Sponsor Guidelines:	https://wellcomeleap.org/the-missed-vital-sign/
UM Nominations Process:	The University of Minnesota Foundation and the Research and Innovation Office collaborate to provide resources to applicants who would like to pursue Wellcome Leap funding opportunites. Prior to woking on the abstract, please share an expression of interest that will be reviewed by RIO and Academic leadership. Include a one to two paragraph summary of your research that aligns with the opportunity to lonelson@umn.edu and meaghanv@umn.edu no later than 5pm on 4/30. You will then recieve the required documents for submission and support for proposal submission. For more information, please contact Foundation Engagement Associate, Logan Nelson at lonelson@umn.edu.
Peer Review Coordination:	University of Minnesota Foundation contact email
Status:	Open
Please note:	To be considered for peer review and internal selection, faculty must follow the above submission guidelines and meet the UM deadline as set by the office coordinating the peer review for this opportunity.

General Information

Each posting has information about the external sponsor and opportunity as well as the internal application instructions.
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Column Descriptions

Sponsor: redirects you to the sponsor's main website
Title/Guidelines: redirects you to sponsor specific information regarding the opportunity which may include description, eligibility, budget instructions, forms and other requirements
Amount: Maximum dollar amount awarded.
Add’l Req: Identifies special requirements such as cost sharing, partners, etc.
Sponsor Deadline: External deadline identified by the sponsor.
UM Submission Instructions: Contains specific internal submission requirements including internal proposal instructions, deadline, eligibility, internal nomination process, contact information.
# Apps: The maximum number of applications the sponsor will allow the university to submit.
UM Deadline: Submission deadline for internal proposal as determined by the coordinating office.
Status:
- Open: UM deadline has not passed and the opportunity is open for application.
- In Review: Peer review process is in progress for the opportunity.
- PI Selected: The PI has been selected as the official UM nominee.
- Closed: Sponsor deadline has passed and the opportunity is closed for application.

U of M Submission Instructions (Required)

This link includes summary sponsor information, specific instructions for internal submission and contact information for the university office coordinating the nomination process.

Follow the directions in the submission instructions and submit required materials by the UM deadline to the contact indicated.
Instructions vary according to the requirements of the sponsor and the university office coordinating the nomination process.

Registration (optional)

Registration is an optional but highly recommended feature. Perhaps you are looking for a wider audience for your proposal idea, or for potential collaborators to work with to create a stronger application. Registration allows applicants to share proposal ideas and post contact information.

Registration also provides information that helps the university office overseeing the nomination to determine the level of coordination needed and guide the review process.

To register (or view registrants), click on the UM Submission Instructions for a specific opportunity, then click on the Register Interest link.

Selection Process

Once the internal deadline has passed, the status will change to “In Review” and proposals will undergo review.
If there are multiple applicants, the office managing the nomination will determine the review criteria and coordinate the review process.
Once review has been completed all parties will be notified via email.
Nominees will be provided with a letter addressed to the sponsor from the RIO indicating that they are the university's nominee. This letter should accompany the nominee's proposal.
SPA is notified of the university's nominee(s) and the status is updated to “PI Selected”.

*If you have questions about the University's process related to extramural funding opportunities requiring nomination or if you have any technical issues with the site, contact collabor8@umn.edu.